Introduction to the immune system Updated for 2024

Updated: May 4, 2024



What is the immune system? The immune system is made up of organs, tissues, cells, and molecules that all work together to generate an immune response that …

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33 Comments on “Introduction to the immune system Updated for 2024”

  1. Holy shit, so what you're saying is that we have little kamikaze agents inside our body called neutrophils and a sort of pearl harbour is happening inside us all?

  2. Nothing was said about how autoimmunity develops, nor, as he started out, showing how cancer cells that normally show up in the body on occasion, are attacked and removed from tissue. This kind of presentation is the standard medical school way of teaching, lots and lots of unnecessary facts, to shape the poor medical student's psyche to surrendering to "those in the know", regurgitating endless technical facts from this lab and that lab and every other lab, so finally the student will become an obedient zombie who will prescribe lab drugs that work on one of these isolated facts without reasoning further, because more reasoning, or reasoning on your own, will cause this incredible complexity to collapse, they'll have you think. Is it not simply better to seek or understand how certain plants, in and of their own capability, can destroy the problem in the 1st place? But of course that would defeat the whole purpose, which is to "train" the student, rather than teach him via curiosity and original thinking, because then he may decide the pharmaceutical approach is ridiculous, expensive, let alone with harmful side-effects they never speak of, let alone marginally as effective as God's natural formulas.

  3. There is a problem with the diagram of a CD4 cell in outlining the immune response to a bacterium in the lungs. It seems as if the Help T has immunoglobins on it surface. It there was not sound it looks like a B cell is binding to another B cell.

  4. Thank u so much osmosis for making it easy especially the MHC part u made it easy by saying served on silver platter .
    Kudos to ur team grateful

  5. Antibody immunoglobulin circulate blood float freely humoral immunity body fluid T cells mature T cell DCs CD markers CD3+ CD4+ MHC2 CD3+ CD8+ MHC1 pass Epithelium RM ingest bacteria cytokine secretion Eos Neu ly,ph node B cell directly

  6. Thanks so much for exsplaing that to me in a way that I understood. I sort of know already,but it’s good to remind yourself every now and again.I wasn’t going to mention it,but I did also originally look at this allong with all of this corona virus epidermic that’s going on at the moment. Oh and let me just say that I hope you and everyone you know all stay safe and be well whilst this horrible virus passes.

  7. The complexity and choreography of all these immune cells working
    together in such a coordinated fashion is truly beyond awe. It's like
    micro miracles are happening inside of us every day by the millions.
    This brings to mind what happens when things go wrong. Take cancer for
    example. Is the primary reason for cancer merely "something going wrong"
    in the immune system? Or does a perfectly healthy immune system just
    get overwhelmed by sheer numbers of cancer cells due to some other
    "unrelated?" reason? Also, when chemo is used, it obviously directly
    kills cancer cells, oft times very effectively in the first round. But
    it must also kill off the immune system cells, leaving the patient's
    immune system cells devastated, and unable to fight the return of new
    cancer cells. Frankly, poisoning all cells in the body to treat ANYTHING
    seems to be about the dumbest idea I've ever heard. By the way, I
    don't have cancer, in case you were wondering.

  8. The complexity and choreography of all these immune cells working
    together in such a coordinated fashion is truly beyond awe. It's like
    micro miracles are happening inside of us every day by the millions.
    This brings to mind what happens when things go wrong. Take cancer for
    example. Is the primary reason for cancer merely "something going wrong"
    in the immune system? Or does a perfectly healthy immune system just
    get overwhelmed by sheer numbers of cancer cells due to some other
    "unrelated?" reason? Also, when chemo is used, it obviously directly
    kills cancer cells, oft times very effectively in the first round. But
    it must also kill off the immune system cells, leaving the patient's
    immune system cells devastated, and unable to fight the return of new
    cancer cells. Frankly, poisoning all cells in the body to treat ANYTHING
    seems to be about the dumbest idea I've ever heard. By the way, I
    don't have cancer, in case you were wondering.

  9. Neutrophiles, basophiles, eosinophiles, and mast cells: basic police force.

    Macrophages and dendritic cells: sentinels posted around the perimeter of the body. They are monocytes patrolling the streets, who then got promoted to leave the streets and keep guard in the tissues.

    T Cells: generals in the battlefield, although first they need to be trained in the headquarters (thymus and lymph nodes) and be presented with the enemy to be able to recognize them. CD4+ help to coordinate the attacks and CD8+ help to execute them, especially against viruses.

    B Cells: highly respected soldiers who can use very effective weapons (antibodies), and they don't even need to be presented with the enemy first to work. They get promoted to plasma cells by their generals, so they become able to deploy their effective weapons on the field.

    Natural killer cells: CD8+ T cells that became rough agents and prefered to work alone, with no restriction or coordination imposed by other cells. They ride in motorcycles and drink whisky at bars.

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